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Dopamine Regulates Insulin Secretion Through a Complex of Receptors, Finds New Study

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June 27, 2022

D1 receptor antagonists reversed DA-mediated inhibition

D1 receptor antagonists reversed DA-mediated inhibition

In a leap forward for diabetes research, Tokyo Tech researchers reveal that the feel-good hormone, dopamine, regulates insulin secretion through a heteromeric complex of receptors, thereby providing new targets for antidiabetic medication and therapy. The study is the first to elucidate the mechanism behind dopamine's down-regulation of insulin secretion.

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