Life Science and Technology News
Life Science and Technology
Associate professor Masahiro TAKINOUE
|Office||Room 1806, J2 building, Suzukakedai campus|
|Degree||Ph.D.2007, Department of Physics, The University of Tokyo|
|Areas of Research||Biophysics, DNA Nanotechnology, Synthetic Biology, Soft Matter Physics, Molecular Robotics, Microfluidcs|
|Keywords||Artificial cells, Artificial nuclei, DNA gel, DNA origami, Microdroplet|
|Web site||Takinoue Lab.|
The life system is one of the most complex systems in nature. We can see dynamical autonomous behaviors, emergence of functional behaviors, and also intelligence in the life systems unlike non-living systems. Although the Life systems are complex, the life systems are also composed of usual matter same as non-living systems. The research themes of our lab are basically inspired by such physical point of view of life systems.
Our group studies the construction of bio-inspired dynamical self-organized systems (molecular robots, artificial cells) using information molecules such as DNA. Through their construction, we are challenging to understand "What is Life?" from a physical point of view about nano/micro-scale autonomous systems and to invent novel post-silicon computing-based intelligent molecular machines, molecular computers, and molecular robots with sophisticated functions beyond life systems.
We are challenging to construct autonomous nano/micrometer-sized "molecular robots" and "molecular computers". Molecular robots and molecular computers are made of biopolymers and biomaterials such as DNA, protein, lipids, etc. The Molecular robots and molecular computers have autonomously working sensors, processors, and actuators. They can work in microscopic spaces like inside of cells and can be applied to medical systems, tiny machines, etc.
We are constructing "artificial cells" using biomolecules (DNA, RNA, protein, lipid, etc.) to understand essential aspect of life systems. Life systems exhibit dynamical behavior such as autonomous sensing, autonomous information processing, autonomous motion, etc. Artificially constructing cell-like systems is important not only for basic science (physics, chemistry, biology) but also for applied science and engineering.