Life Science and Technology News

【Labs spotlight】 Hisabori and Wakabayashi Laboratory(until Mar. 2023)

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October 18, 2018

The Department has a variety of laboratories for Life Science and Technology, in which cutting-edge innovative research is being undertaken not only in basic science and engineering but also in the areas of medicine, pharmacy, agriculture, and multidisciplinary sciences.

This "Spotlight" series features a laboratory from the Department and introduces you to the laboratory's research projects and outcomes. This time we focus on Hisabori and Wakabayashi Laboratory.

※Professor Hisabori and Associate Professor Wakabayashi retired from Tokyo Tech on March 31, 2023.

Professor Hisabori and Associate Professor Wakabayashi

Life Science and Technology
Professor Toru Hisaboriouter
Associate Professor Ken-ichi Wakabayashiouter

Degree Professor Toru Hisabori : PhD 1985, Waseda University
Associate Professor Ken-ichi Wakabayashi : Ph.D. 2001, University of Tokyo
Areas of Research Plant Biochemistry, Bioenergetics,
Cell Motility, Photomovement of microorganisms
Keywords ATP synthase, redox regulation, thioredoxin
Cilia, Flagella, Phototaxis, Redox regulation
Website Hisabori and Wakabayashi Laboratoryouter

Research interest

Molecular mechanisms of rotation and regulation of ATP synthase from photosynthetic organisms

(1) Molecular mechanisms of rotation and regulation of ATP synthase from photosynthetic organisms

(2) Biochemical analysis of thioredoxin and its target proteins in photosynthetic organisms

(3) Anti-oxidant stress system in photosynthetic organisms

(4) Regulatory mechanisms for Chlamydomonas photomovements

(5) Regulatory mechanisms for eukaryotic ciliary/flagellar movements

(A) Chlamydomonas cell and (B) its schematic. It has two flagella, one cup-shaped chloroplast surrounding the nucleus, and one eyespot. (C) Schematic of the eyespot, the directional photoreceptor. Light reflection at the carotenoid-rich granule layers amplifies the light from the outside for channelrhodopsins, the photoreceptor proteins, and blocks the light from the inside. (D) Photobehaviors of Chlamydomonas. When illuminated with weak light, it shows positive or negative phototaxis. When illuminated with sudden strong light, it changes its flagellar waveform and swims backward (photoshock response).

Selected publications

Publication in English

Hisabori-Wakabayashi Lab.別窓

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