【Labs spotlight】 Suzuki Laboratory
Breaking genetic codes in neuronal circuit
The Department has a variety of laboratories for Life Science and Technology, in which cutting-edge innovative research is being undertaken not only in basic science and engineering but also in the areas of medicine, pharmacy, agriculture, and multidisciplinary sciences.
This "Spotlight" series features a laboratory from the Department and introduces you to the laboratory's research projects and outcomes. This time we focus on Suzuki Laboratory.
Research findings
Selected publications
- Activity-dependent synaptic plasticity
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- 1.Sugie A, Hakeda-Suzuki S, Suzuki E, Silies M, Shimozono M, Mohl C, Suzuki T*, Tavosanis G*.(2015) Molecular Remodeling of the Presynaptic Active Zone of Drosophila Photoreceptors via Activity-Dependent Feedback. Neuron. 2015 May 6;86(3):711-25. (2015)
- 2.Berger-Muller, S., Sugie, A., Takahashi, F., Tavosanis, G., Hakeda-Suzuki, S., Suzuki, T. Assessing the role of cell-surface molecules in central synaptogenesis in the Drosophila visual system. PLos One. Dec 26;8(12):e83732 (2013)
- Axon guidance and synaptic-layer targeting
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- 3.Mann, K., Wang, M., Luu, S-H., Ohler, S., Hakeda-Suzuki, S., Suzuki, T. A putative tyrosine phosphorylation site of the cell surface receptor Golden goal is involved in synaptic layer selection in the visual system. Development Feb;139(4):760-71 (2012)
- 4.Hakeda-Suzuki, S.*, Berger-Mueller, S.*, Usui, T., Horiuchi, S., Uemura, T., Suzuki, T. Golden Goal Collaborates with Flamingo in Conferring Synaptic-Layer Specificity in the Visual System. Nature Neuroscience 3:314-24 (2011)
- 5.Ohler, S., Hakeda-Suzuki, S., Suzuki, T. Hts, the Drosophila homologue of Adducin, physically interacts with the transmembrane receptor Golden goal to guide photoreceptor axons. Developmental Dynamics 240: 135-148. (2011)
- 6.Berger J, Senti K, Senti G, Newsome T, Asling B, Dickson BJ, Suzuki T. Systematic Identification of Genes that Regulate Neuronal Wiring in the Drosophila Visual System. PLoS Genetics 4(5): e1000085.doi:10.1371/ journal.pgen.1000085 (2008)
- 7.Tomasi, T.*, Hakeda-Suzuki, S.*, Ohler, S., Schleiffer, A., Suzuki, T. The transmembrane protein Golden Goal regulates R8 photoreceptor axon-axon and axon-target interactions. Neuron 57: 691-704 (2008)
- 8.Maurel-Zaffran C*, Suzuki T*, Gahmon G, Treisman JE, Dickson BJ. Cell-Autonomous and -Nonautonomous Functions of LAR in R7 Photoreceptor Axon Targeting. Neuron 32: 225-235 (2001)
- 9.T Berger J*, Suzuki T*, Senti K-A, Stubbs J, Schaffner G, Dickson BJ. Genetic mapping with SNP markers in Drosophila. Nature Genetics 29: 475-481 (2001)
*Find more about the lab and the latest activities at the lab site.