Event Information

Precision and Connectivity in Transcription and Translation

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Date
Tuesday, July 18, 2017
Time
16:00 - 17:30
Venue

Suzukakedai Campus, Tokyo Institute of Technology別窓
B2 Bldg, Room 426

Speaker
Prof. Rivka Dikstein. The Weizmann Institute of Science (Rehovot, Israel)
Contact
Yuki Yamaguchi
School of Life Science and Technology
(ext. 5798)

Our research is focused on elucidation of the means by which regulatory information encoded within the genes is decoded during transcription and translation and to reveal the connections between the two processes. To address these issues we utilize several biological systems. One is NF-κB, a major proinflammatory transcription factor. A subset of inflammatory-response NF-κB target genes is activated extremely fast following pro-inflammatory signal. I will describe our findings regarding a novel role of the transcription elongation factor Spt5 in linking promoter-escape, chromatin modifications and TFIID recruitment, all of which are necessary for transcription re-initiation and rapid induction of inflammatory-response genes. I will also describe our findings about translation initiation mechanisms that are linked to transcription.

Precision and Connectivity in Transcription and Translation flyer (Japanese)

Precision and Connectivity in Transcription and Translation flyer (Japanese)

Update : July 14, 2017

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