Life Science and Technology News

Labs spotlight #44 - Kajiwara Laboratory -

Medical Microbiology & Environmental Biotechnology

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April 13, 2017

The Department has a variety of laboratories for Life Science and Technology, in which cutting-edge innovative research is being undertaken not only in basic science and engineering but also in the areas of medicine, pharmacy, agriculture, and multidisciplinary sciences.

This "Spotlight" series features a laboratory from the Department and introduces you to the laboratory's research projects and outcomes. This time we focus on Kajiwara Laboratory.

Professor Susumu Kajiwara

Human Centered Science and Biomedical Engineering
Professor Susumu Kajiwaraouter

Degree PhD 1993, Tokyo Institute of Technology
Areas of Research Medical Microbiology, Molecular Biotechnology, Environmental Science.
Keywords Pathogenicity, Drug resistance, Biofilm, Drug discovery, Biofuel
Website Kajiwara Laboratoryouter

Research interest

Our laboratory has studied in the field medical microbiology and environment biotechnology and, in present, focuses on "drug discovery for infectious diseases", "the molecular mechanism of drug resistance and biofilm formation of pathogens", the interaction mechanism between pathogen and the host" and "the efficient utilization of unused bio-resources".

Biofilm formation of pathogenic fungus

Biofilm formation of pathogenic fungus

Biofilm formation of pathogenic fungus

Apoptosis induction of hepatocyte by pathogenic fungi

Apoptosis induction of hepatocyte by pathogenic fungi

Apoptosis induction of hepatocyte by pathogenic fungi

Selected publications

  • [1] W. Watanasrisin et al. "Identification and characterization of Candida utilis multidrug efflux transporter CuCdr1p" FEMS Yeast Res. 16 pii: fow042. doi: 10.1093/femsyr/fow042 (2016)
  • [2] S. Panapruksachat et al. "Identification and functional characterization of Penicillium marneffei pleotropic drug resistance transporters ABC1 and ABC2" Medical Mycol. 54, 478- (2016)
  • [3] W. Juntachai, et al. "Identification of the haemolytic activity of Malassezia species" Mycoses 57, 163-168 (2014)
  • [4] S. Youngchim, et al. "The role of L-DOPA on melanization and mycelial production in Malassezia furfur" PLoS One 8, e63764 (2013)
  • [5] M. Nagi, et al. "The Candida glabrata sterol scavenging mechanism, mediated by the ATP-binding cassette transporter Aus1p, is regulated by iron limitation" Mol Microbiol. 88, 371-381 (2013)
  • [6] C. Yurayart, et al. Antifungal susceptibilities and interpretation analysis of Malassezia pachydermatis and Candida parapsilosis isolated from healthy and dogs with seborrheic dermatitis" Medical Mycol. 51, 721-730 (2013)
  • [7] M. Nagi, et al. "The Candida glabrata sterol scavenging mechanism, mediated by the ATP-binding cassette transporter Aus1p, is regulated by iron limitation" Mol Microbiol. 88, 371-381 (2013)
  • [8] A. Thong-on, et al, "Isolation and characterization of anaerobic bacteria for symbiotic recycling of uric acid nitrogen in the gut of various termites", Microbes Envrion. 27, 186-192 (2012)
  • [9] W. Juntachai, et al. "Purification and characterization of a secretory lipolytic enzyme, MgLIP2, from Malassezia globosa", Microbiology 157, 3490-3497 (2011)
  • [10] T. Akao, et al. "Whole-genome sequencing of sake yeast Saccharomyces cerevisiae Kyokai no. 7", DNA Res. 18, 423-434 (2011)
  • [11] C. Yurayart, et al. "Comparative analysis of frequency, distribution and population sizes of yeasts associated canine seborrheic dermatitis and healthy," Veterinary Microbiology, 148, 356-362 (2011)
  • [12] M. Nagi, et al. "Transcription factors CgUPC2A and CgUPC2B regulate ergosterol biosynthetic genes in Candida glabrata," Genes to Cells, 16, 80-89 (2011)

Contact

Professor Susumu Kajiwara
Room 1018, J3 building, Suzukakedai campus
E-mail : kajiwara.s.aa@m.titech.ac.jp

*Find more about the lab and the latest activities at the lab siteouter.

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